Gamma-hydroxybutyric acid (GHB) withdrawal: a case report
| Autor: | Peter Roy-Byrne, W. R. Murray Bennett, Lawrence G. Wilson |
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| Rok vydání: | 2007 |
| Předmět: |
Drug
Adult Male Recreational Drug Sodium Oxybate Addiction media_common.quotation_subject Medicine (miscellaneous) Hydroxybutyrates gamma-Hydroxybutyric acid Substance Withdrawal Syndrome Benzodiazepines Neurochemical Olanzapine Anesthesia medicine Humans Treatment Failure Withdrawal syndrome Psychology General Psychology medicine.drug media_common Adjuvants Anesthesia Antipsychotic Agents |
| Zdroj: | Journal of psychoactive drugs. 39(3) |
| ISSN: | 0279-1072 |
| Popis: | GHB is an increasingly popular drug of abuse that can be associated in select cases with growing dependence and a severe withdrawal syndrome. While benzodiazepines are recommended for treatment of the withdrawal syndrome, some cases have been described as benzodiazepine-resistant. The authors describe treatment of such a case, which was unsuccessfully treated initially with benzodiazepines, then successfully treated with adjuvant atypical neuroleptics, and offer a possible neurochemical explanation for why such agents may be theoretically more effective than benzodiazepines in treating GHB withdrawal. |
| Databáze: | OpenAIRE |
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