Outcomes of Bariatric Surgery in Morbidly Obese Patients with Multiple Sclerosis
| Autor: | Philip R. Schauer, Stacy A. Brethauer, Adham Jammoul, Ali Aminian, Kalman P. Bencsath, Carolyn J. Fisher, Alexander Rae-Grant, Hideharu Shimizu |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male lcsh:Internal medicine Sleeve gastrectomy medicine.medical_specialty Multiple Sclerosis Article Subject Endocrinology Diabetes and Metabolism medicine.medical_treatment Gastric bypass Population Gastric Bypass Morbidly obese 03 medical and health sciences 0302 clinical medicine Postoperative Complications Weight loss Surveys and Questionnaires Weight Loss medicine Humans In patient 030212 general & internal medicine lcsh:RC31-1245 education Ohio Retrospective Studies education.field_of_study business.industry Multiple sclerosis Middle Aged medicine.disease Obesity Surgery Obesity Morbid Treatment Outcome Case-Control Studies Female medicine.symptom business 030217 neurology & neurosurgery Research Article |
| Zdroj: | Journal of Obesity Journal of Obesity, Vol 2017 (2017) |
| ISSN: | 2090-0716 |
| Popis: | Obesity is common in patients with multiple sclerosis (MS); however, safety and efficacy of bariatric surgery in this population remain unclear. A database of 2,918 was retrospectively reviewed, yielding 22 (0.75%) severely obese patients with MS who underwent bariatric surgery. Sixteen surgical patients with complete follow-up data were matched to a nonsurgical control group of MS patients, based on age, BMI, MS subtype, and length of follow-up. MS relapse rates and trends in the timed twenty-five foot walk test (T25FW) were compared. In the surgical group (gastric bypass n=19, sleeve gastrectomy n=3), preoperative BMI was 46.5 ± 7.2 Kg/m2 and average excess weight was 60.4 kg. Follow-up data was collected at 59.0 ± 29.8 months. There were two major and four minor complications. Five patients required readmission and there were no mortalities. Percent excess weight loss was 75.5 ± 27.0%. In the 16 patients with follow-up data, patients who underwent bariatric surgery were significantly faster on the T25FW compared to the nonsurgical population. In conclusion, bariatric surgery is relatively safe and effective in achieving weight loss in patients with MS. In addition, surgery may help patients maintain ambulation. Findings support the need for further studies on bariatric surgery and disease-specific outcomes in this population. |
| Databáze: | OpenAIRE |
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