Renal tubular function and urinary acidification capacity in early juvenile diabetes
| Autor: | Mateos Antón F, Grande C, García Puig J, Luis Felipe Pallardo, Gil A, Francisco Arnalich, J J Vázquez, Montero A, Gaspar G |
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| Rok vydání: | 1981 |
| Předmět: |
Glycosuria
Male medicine.medical_specialty Adolescent Endocrinology Diabetes and Metabolism Potassium Sodium Urinary system Clinical Biochemistry chemistry.chemical_element Renal function urologic and male genital diseases Biochemistry Excretion chemistry.chemical_compound Electrolytes Endocrinology Internal medicine medicine Humans Child Biochemistry (medical) Osmolar Concentration General Medicine Uric Acid Renal Elimination Diabetes Mellitus Type 1 Kidney Tubules chemistry Uric acid Female medicine.symptom Glomerular Filtration Rate |
| Zdroj: | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 13(11) |
| ISSN: | 0018-5043 |
| Popis: | Renal elimination of uric acid, calcium, phosphorus, sodium, potassium, chloride and magnesium and urinary acidification capacity were determined in ten insulin-dependent diabetics and in ten matched control subjects. The diabetics showed excessive excretion of uric acid, sodium, potassium, chloride and ammonia. Sodium, chloride and ammonia excretion fractions was also increased with respect to controls. The enhanced excretion of these substances in diabetics failed to relate to glomerular filtration rate, glycosuria or insulin requirements. These findings might be explained on the basis of glomerular filtration rate elevation, tubular response to this increment, and the underlying metabolic disturbances of diabetes. |
| Databáze: | OpenAIRE |
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