Towards CRISPR powered electrochemical sensing for smart diagnostics
| Autor: | K. Sudhakara Prasad, Jospeh Sonia, Kannan Sapna, Poyye Dsouza Priya Swetha |
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| Rok vydání: | 2021 |
| Předmět: |
2019-20 coronavirus outbreak
Coronavirus disease 2019 (COVID-19) Biosensing Computer science Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) High selectivity Electrochemical Nanotechnology Context (language use) Review Article Analytical Chemistry CRISPR/Cas Point-of-care Electrochemistry Electrochemical biosensor CRISPR E-CRISPR |
| Zdroj: | Current Opinion in Electrochemistry |
| ISSN: | 2451-9103 |
| DOI: | 10.1016/j.coelec.2021.100829 |
| Popis: | Even though global health has been steadily improved, the global disease burden associated with communicable and non-communicable diseases extensively increased healthcare expenditure. The present COVID-19 pandemic scenario has again ascertained the importance of clinical diagnostics as a basis to make life-saving decisions. In this context, there is a need for developing next-generation integrated smart real-time responsive biosensors with high selectivity and sensitivity. The emergence of clustered regularly interspaced short palindromic repeats (CRISPR)/Cas biosensing systems has shown remarkable potential for developing next-generation biosensors. CRISPR/Cas integrated electrochemical biosensors (E-CRISPR) stands out with excellent properties. In this opinionated review, we illustrate the rapidly evolving applications for E-CRISPR-integrated detection systems towards biosensing and the future scope associated with E-CRISPR based diagnostics. Graphical abstract Image 1 |
| Databáze: | OpenAIRE |
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