Contrast-enhanced spectral mammography without and with a delayed image for diagnosing malignancy among mass lesions in dense breast
| Autor: | Dilyara Kaidarova, Alexandra Sergeevna Panina, Natalya Igorevna Inozemtceva, Akmaral Ainakulova, Zhanar Zhakenova, Madina Orazaykyzy Gabdullina, Zhamilya Zholdybay, Dias Toleshbayev, Jandos Amankulov |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
dense breast
Malignancy breast lesions 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Breast cancer breast cancer Medicine Mammography Radiology Nuclear Medicine and imaging Original Paper Suspicious for Malignancy Breast tissue medicine.diagnostic_test business.industry Area under the curve Washout medicine.disease Oncology 030220 oncology & carcinogenesis Differential diagnosis business Nuclear medicine contrast-enhanced spectral mammography |
| Zdroj: | Contemporary Oncology Contemporary Oncology, Vol 25, Iss 1, Pp 17-22 (2021) |
| ISSN: | 1897-4309 1428-2526 |
| Popis: | Aim of the study To analyse the diagnostic performance of contrast-enhanced spectral mammography (CESM) based on morphologic and enhancement patterns of mass lesions in dense breast using different protocols: CESM without delayed image and CESM with delayed image. Material and methods A total of 151 informed women with suspicious for malignancy mass lesions in dense breast were included in this study. All of them underwent CESM using 2 protocols. A total of 155 lesions were pathomorphologically verified. We analysed morphologic patterns on low-energy (LE) images and recombined images (RI) by defining the shape, margin, and dynamic patterns based on delayed images. Results The comparative analysis revealed that the shape and margins on RI were more significant than those on LE images. The dynamic indicators of CESM were found to be highly significant in dense breasts. The correlation between kinetic curve and histological results demonstrated that a persistent type of curve was common for benign lesions, accounting for 15/22 (68.1%); plateau and washout - for malignant lesions, accounting for 24/89 (26.9%) and 61/89 (68.5%), respectively. Delayed image leads to an increase of specificity up to 12.4%, which is statistically significant. The area under the curve (AUC) in CESM with delayed image is larger than that in CESM without delayed image (p < 0.01). Conclusions CESM is sensitive for the differential diagnosis of breast lesions. CESM with delayed image has higher specificity than CESM without delayed image. Delayed images with plateau and washout are typical for malignancy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|