Bone mineral density in patients with systemic sclerosis and its association with hand involvement

Autor: Amira A. Shahin, Waleed Gomaa, Safaa Sayed, Hania S. Zayed
Rok vydání: 2013
Předmět:
Zdroj: The Egyptian Rheumatologist. 35(4):233-238
ISSN: 1110-1164
DOI: 10.1016/j.ejr.2013.08.001
Popis: Aim of the workThe aim of the present study is to assess bone mineral density (BMD) in systemic sclerosis (SSc) patients and to determine associated factors.Patients and methodsSixty-five female SSc patients (mean age 39.5±13.5years, disease duration 7.3±5.9years), and forty age- and sex- matched controls were included. Forty-seven patients had limited SSc and 18 had diffuse type. Patients were subjected to clinical and functional assessment. BMD was quantified at the distal radius, femoral neck and lumbar spine (L2–4) by dual energy X-ray absorptiometry.ResultsSSc patients had a higher frequency of osteoporosis at the distal radius and osteopenia at the lumbar spine (p=0.001 and 0.002, respectively), but the BMD at the femoral neck was not significantly different from the control group. Patients with osteoporosis at the distal radius had a significantly higher frequency of hand deformities (p
Databáze: OpenAIRE