Integration of FDG- PET/CT into external beam radiation therapy planning
Autor: | U. Pietrzyk, Wim J.G. Oyen, John Aldo Lee, Andrea Schaefer, Daniela Thorwarth, Aleksandar Grgic, Ronald Boellaard, W. Van Elmpt, Wouter V. Vogel, Thomas Beyer, Bernhard Sattler, Dirk De Ruysscher, Ursula Nestle |
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Rok vydání: | 2012 |
Předmět: |
medicine.medical_specialty
Standardization Therapy planning Context (language use) Multimodal Imaging 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Fluorodeoxyglucose F18 medicine Humans Radiology Nuclear Medicine and imaging Medical physics Radiation treatment planning Protocol (science) PET-CT medicine.diagnostic_test business.industry Radiotherapy Planning Computer-Assisted Radiotherapy Dosage General Medicine Translational research Pathogenesis and modulation of inflammation [ONCOL 3] Systems Integration Workflow Positron emission tomography Positron-Emission Tomography 030220 oncology & carcinogenesis Radiopharmaceuticals Radiotherapy Conformal Tomography X-Ray Computed business Algorithms Radiotherapy Image-Guided |
Zdroj: | Nuklearmedizin. Nuclear Medicine, 51, 4, pp. 140-53 Nuklearmedizin. Nuclear Medicine, 51, 140-53 |
ISSN: | 2567-6407 0029-5566 |
Popis: | SummaryThis work addresses the clinical adoption of FDG-PET/CT for image-guided radiation therapy planning (RTP). As such, important technical and methodological aspects of PET/CTbased RTP are reviewed and practical recommendations are given for routine patient management and clinical studies. First, recent developments in PET/CT hardware that are relevant to RTP are reviewed in the context of quality control and system calibration procedures that are mandatory for a reproducible adoption of PET/CT in RTP. Second, recommendations are provided on image acquisition and reconstruction to support the standardization of imaging protocols. A major prerequisite for routine RTP is a complete and secure data transfer to the actual planning system. Third, state-of-the-art tools for image fusion and co-registration are discussed briefly in the context of PET/CT imaging preand post-RTP. This includes a brief review of state-of-the-art image contouring algorithms relevant to PET/CT-guided RTP. Finally, practical aspects of clinical workflow and patient management, such as patient setup and requirements for staff training are emphasized. PET/ CT-guided RTP mandates attention to logistical aspects, patient set-up and acquisition parameters as well as an in-depth appreciation of quality control and protocol standardization. Conclusion: Upon fulfilling the requirements to perform PET/CT for RTP, a new dimension of molecular imaging can be added to traditional morphological imaging. As a consequence, PET/CT imaging will support improved RTP and better patient care. This document serves as a guidance on practical and clinically validated instructions that are deemed useful to the staff involved in PET/CT-guided RTP. |
Databáze: | OpenAIRE |
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