Thyroid nodules in acromegaly

Autor: Rosa Laudi, Alicia Lowenstein, Marcelo Junco, Patricia Glikman, Amelia Rogozinski, Alejandra Furioso, Adriana Reyes
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Arquivos Brasileiros de Endocrinologia & Metabologia v.56 n.5 2012
Arquivos Brasileiros de Endocrinologia & Metabologia
Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron:SBEM
Popis: OBJECTIVE: We made a prospective study evaluating the prevalence of thyroid nodular disease in acromegalic patients. SUBJECTS AND METHODS: Thyroid ultrasound and ultrasound-guided fine needle aspiration biopsy were performed when nodules were detected. Nodules were characterized by cytology and histopathology. RESULTS: We found high prevalence of nodular thyroid disorder, 23/34 (67%) in acromegalic patients. High risk and malignant cytology were significantly higher in acromegalic patients than in our non-acromegalic population (25% vs. 9%). Differentiated thyroid carcinoma was present in 11% of the acromegalic patients. CONCLUSIONS: We strongly recommend periodic thyroid evaluation by ultrasound in patients with acromegaly. Fine needle aspiration biopsy should be performed in nodules larger than 10 mm, and in all suspicious nodules, regardless of the size.
Databáze: OpenAIRE