Injection of freshly collected autologous adipose tissue into non-healing wounds after closed incision pilonidal surgery
| Autor: | A. G. Pedersen, M. J. Sørensen, S. Haas, L Lundby |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Pilonidal disease medicine.medical_specialty Adipose tissue Pilot Projects Abdominal wall Young Adult 03 medical and health sciences Pilonidal Sinus 0302 clinical medicine Symptom relief medicine Humans In patient Recurrent pilonidal disease Prospective Studies Healing wounds Non-healing wound Autologous fat injection Adipose tissue derived stem cells business.industry Gastroenterology Mean age Colorectal surgery Surgery Treatment Outcome medicine.anatomical_structure Adipose Tissue 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology business Autologous stem cells Abdominal surgery |
| Zdroj: | Haas, S, Sørensen, M J, Lundby, L & Pedersen, A G 2020, ' Injection of freshly collected autologous adipose tissue into non-healing wounds after closed incision pilonidal surgery ', Techniques in Coloproctology, vol. 24, no. 12, pp. 1301-1306 . https://doi.org/10.1007/s10151-020-02276-9 |
| DOI: | 10.1007/s10151-020-02276-9 |
| Popis: | Background: Chronic non-healing wounds are a major problem after closed incision pilonidal surgery. Freshly collected autologous adipose tissue injected into perianal fistulas in patients with Crohn’s disease seems to promote healing. We investigated this technique in patients with non-healing wounds after cleft-lift surgery for pilonidal sinus disease (PSD). Method: In a prospective interventional pilot study conducted at our institution autologous adipose tissue from the abdominal wall was harvested, and injected into chronic non-healing PS wounds after surgical revision, healing rate being the primary outcome. The wounds were left open. Patients were followed every 2 to 3 weeks until complete healing (skin coverage, no undermining). Results: 7 male patients were included (mean age 24 ± 0,6 SD years) and complete healing was achieved in 6 patients (86%). Median time to healing was 90 days (range 36-403 days ) and mean follow-up time was 388± 45 days. All patients reported major symptom relief shortly after the procedure. The mean operation time was 80 ± 23 minutes and the mean amount of freshly collected adipose tissue injected was 27.4± 12 ml. There were no complications. Conclusions: Freshly collected autologous adipose tissue injected into chronic non-healing pilonidal wounds seems safe and efficient. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|