Marked differences in prediabetes- and diabetes-associated comorbidities between men and women-Epidemiological results from a general population-based cohort aged 6-80 years-The LEAD (Lung, hEart, sociAl, boDy) study
| Autor: | Marie-Kathrin Breyer, Emiel F.M. Wouters, Otto C. Burghuber, Sylvia Hartl, Alina Ofenheimer, Daniela Purin, Heinz Drexel, Michael Studnicka, Robab Breyer-Kohansal, Jürgen Harreiter, Julia Altziebler, Christine Heinzle, Frits M.E. Franssen, Alexandra Kautzky-Willer |
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| Přispěvatelé: | RS: NUTRIM - R3 - Respiratory & Age-related Health, Pulmonologie, MUMC+: MA Longziekten (3) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Blood Glucose
Male sex differences Clinical Biochemistry CHILDREN Comorbidity prediabetes 030204 cardiovascular system & hematology Biochemistry Cohort Studies 0302 clinical medicine Epidemiology Medicine 030212 general & internal medicine Prediabetes Myocardial infarction Child Depression (differential diagnoses) Aged 80 and over education.field_of_study COMPLICATIONS diabetes General Medicine Middle Aged DEPRESSION Female epidemiology Cohort study Adult medicine.medical_specialty EUROPE Adolescent Population prevalence comorbidities type-2 Prediabetic State 03 medical and health sciences Young Adult Internal medicine Diabetes mellitus Humans education Aged business.industry medicine.disease INDIVIDUALS RISK-FACTORS business |
| Zdroj: | European Journal of Clinical Investigation, 50(3):13207. Wiley |
| ISSN: | 0014-2972 |
| DOI: | 10.1111/eci.13207 |
| Popis: | Background Based on biological and behavioural diversity sex and gender may affect comorbidities associated with prediabetes and diabetes. Besides evaluating the prevalence of prediabetes and diabetes (using fasting plasma glucose and HbA1(c) levels), the primary aim of the study is to investigate sex and gender differences in the prevalence of comorbidities in subjects with prediabetes and diabetes and to identify possible risk factors associated with prediabetes and diabetes.Design This observational, population-based cohort study included 11.014 subjects aged 6-80 years. Examinations included blood samples, ankle-brachial index, ECG, dual-energy X-ray absorptiometry scan and an interviewer-administered questionnaire.Results Across all ages, prevalence of prediabetes was 20.2% (male 23.6%; female 17.1%), and 5.4% for diabetes (male 7.3%; female 3.7%). The prevalence of prediabetes ranged from 4.4% (6 |
| Databáze: | OpenAIRE |
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