Associations between kidney function and outcomes of comprehensive cardiac rehabilitation in patients with heart failure
| Autor: | Atsuhiko Matsunaga, Shota Uchida, Masashi Yamashita, Junya Ako, Kentaro Kamiya, Nobuaki Hamazaki, Emi Maekawa, Minako Yamaoka-Tojo, Shohei Yamamoto, Takafumi Ichikawa, Ryota Matsuzawa, Kentaro Meguro, Kohei Nozaki |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Renal function Walk Test 030204 cardiovascular system & hematology Kidney Rehabilitation Centers 03 medical and health sciences 0302 clinical medicine Internal medicine Ambulatory Care Humans Medicine In patient Muscle Strength 030212 general & internal medicine Propensity Score Aged Proportional Hazards Models Heart Failure Cardiac Rehabilitation Rehabilitation business.industry Confounding Hazard ratio General Medicine Middle Aged Prognosis medicine.disease Confidence interval Treatment Outcome Heart failure Propensity score matching Cardiology Female Cardiology and Cardiovascular Medicine business Glomerular Filtration Rate |
| Zdroj: | Clinical Research in Cardiology. 111:253-263 |
| ISSN: | 1861-0692 1861-0684 |
| Popis: | To investigate the impact of baseline kidney function on outcomes following comprehensive cardiac rehabilitation (CR) in patients with heart failure (HF). We reviewed a total of 3,727 patients who were admitted for HF treatment. Estimated glomerular filtration rate (eGFR), quadriceps strength (QS), and 6-min walk distance (6MWD) were measured at hospital discharge as a baseline and 5 months thereafter in participants of outpatient comprehensive CR. The association between outpatient CR participation and all-cause events was evaluated using propensity score-matched analysis in subgroups across eGFR stages. The changes in QS and 6MWD following 5-month CR were compared between eGFR stages. Out of the studied patients, 1585 (42.5%) participated in outpatient CR. After propensity matching for clinical confounders, 2680 patients were included for analysis (pairs of n = 1340 outpatient CR participants and nonparticipants). The participation in outpatient CR was significantly associated with low clinical events in subgroups of eGFR ≥ 60 [hazard ratio (HR): 0.65, 95% confidence interval (CI): 0.51–0.84] and eGFR 45–60 (HR: 0.71, 95% CI: 0.55–0.92), but not in eGFR 30–45 (HR: 0.83, 95% CI: 0.64–1.08) and eGFR |
| Databáze: | OpenAIRE |
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