Changes in the dielectric properties of rat lung tissue following x-irradiation
| Autor: | Gamal S. El-Bahy, Abdelrazek B. Abdelrazzak, Ahmad M. Labeeb |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
lcsh:R5-920 Materials science Infrared Biomedical Engineering Modulus Dielectric Biochemistry Genetics and Molecular Biology (miscellaneous) 030218 nuclear medicine & medical imaging 03 medical and health sciences Molecular dynamics 030104 developmental biology 0302 clinical medicine lcsh:Biology (General) Structural Biology Biophysics Dielectric loss Irradiation Fourier transform infrared spectroscopy lcsh:Medicine (General) Spectroscopy lcsh:QH301-705.5 |
| Zdroj: | Egyptian Journal of Basic and Applied Sciences, Vol 5, Iss 4, Pp 298-302 (2018) |
| ISSN: | 2314-808X |
| DOI: | 10.1016/j.ejbas.2018.08.001 |
| Popis: | The Dielectric and Fourier Transform Infrared (FTIR) spectroscopy have been used to investigate the effect of low dose (10 cGy) and high dose (2 Gy) X-rays on the lung of whole-body irradiated rats. The dielectric permittivity ε′, dielectric loss ε″, electric modulus M′ and the imaginary part of the electric modulus M″ measured show changes in the molecular dynamics of the cellular membrane following 10 cGy and 2 Gy-irradiation, reflecting change in the fluidity of the cellular membrane following irradiation, with the most significant change recorded following 2 Gy-irradiation. The FTIR data further illustrate an increase in the fluidity cellular membrane following 10 cGy and 2 Gy-irradiations as marked by the shift and broadening of the CH2 asymmetric stretching vibration band. However, our findings show that 2 Gy-irradiation effects on the cellular membrane were much higher than 10 cGy but they also highlight the considerable effect of radiation dose as low as 10 cGy and its associated risk. Keywords: Ionizing radiation, Dielectric relaxation, Electric modulus, FTIR spectroscopy, Lung tissue |
| Databáze: | OpenAIRE |
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