SARS‐CoV‐2‐specific T cells are generated in less than half of allogeneic HSCT recipients failing to seroconvert after COVID‐19 vaccination

Autor:	Andrea Jarisch, Eliza Wiercinska, Shabnam Daqiq‐Mirdad, Helen Hellstern, Salem Ajib, Anjali Cremer, Ngoc Thien Thu Nguyen, Alexandra Dukat, Evelyn Ullrich, Sandra Ciesek, Kai‐Uwe Chow, Hubert Serve, Erhard Seifried, Peter Bader, Halvard Bonig, Gesine Bug
Rok vydání:	2022
Předmět:	Immunity Cellular COVID-19 Vaccines SARS-CoV-2 T-Lymphocytes Vaccination Immunology Hematopoietic Stem Cell Transplantation COVID-19 Humans Immunology and Allergy Antibodies Viral Immunity Humoral
Zdroj:	European Journal of Immunology. 52:1194-1197
ISSN:	1521-4141 0014-2980
Popis:	Little is known about the cellular immune response to SARS-CoV-2 vaccination in patients after HSCT and B-NHL with iatrogenic B-cell aplasia. In nonseroconverted HSCT patients, induction of specific T-cell responses was assessed. The majority of allogeneic HSCT patients not showing humoral responses to vaccination also fail to mount antigen-specific T-cell responses.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e225e49c5c69cd4e8349f042a93ec791 https://doi.org/10.1002/eji.202149771 Zobrazit plný text záznamu Plný text