Hyperpigmentation mimicking Laugier syndrome, levodopa therapy and Addison's disease
| Autor: | A. Miranda Romero, MV Torrero, J Vega Gutiérrez, Gloria Martínez, M López de Juan |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Levodopa
medicine.medical_specialty Hydrocortisone Mucocutaneous zone Hand Dermatoses Dermatology Vulva Diagnosis Differential Addison Disease Hyperpigmentation medicine Humans Sex organ Oral mucosa Aged Foot Dermatoses business.industry Mouth Mucosa Levodopa therapy Parkinson Disease Syndrome Laugier–Hunziker syndrome medicine.disease Infectious Diseases medicine.anatomical_structure Fludrocortisone Addison's disease Female medicine.symptom business medicine.drug |
| Zdroj: | Journal of the European Academy of Dermatology and Venereology. 17:324-327 |
| ISSN: | 1468-3083 0926-9959 |
| DOI: | 10.1046/j.1468-3083.2003.00431.x |
| Popis: | The Laugier-Hunziker syndrome is an acquired, idiopathic, benign mucocutaneous hypermelanosis that usually occurs on the lips and oral mucosa, although it may appear at other sites. Nails are frequently involved, mainly forming longitudinal hyperpigmented bands. We report the case of a patient that presented a typical picture of this entity, nearly 1 year after the beginning of treatment with levodopa. Two years after the first lesions occurred, she developed Addison's disease. The patient suffered from a diffuse discrete hyperpigmentation (it was more remarkable on exposed areas) and an intensification of the melanotic macules that were previously noticeable before in oral and genital mucosa, fingers, toes and nails. Hormonal replacement treatment enabled the control of laboratory and general manifestations and to decrease the degree of mucocutaneous hyperpigmentation considerably, despite initial hyperpigmented lesions persisting in described areas. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text