Squamous cell carcinoma antigen concentration in fine needle aspiration samples

Autor: Anna C. Muller Kobold, Jeroen E. van Schaik, Boudewijn E. C. Plaat, Bert van der Vegt, Bernard F. A. M. van der Laan, Bettien M. van Hemel
Přispěvatelé: Man, Biomaterials and Microbes (MBM), Damage and Repair in Cancer Development and Cancer Treatment (DARE), Guided Treatment in Optimal Selected Cancer Patients (GUTS), Targeted Gynaecologic Oncology (TARGON)
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Male
Pathology
Squamous cell carcinoma Antigen
HNSCC
0302 clinical medicine
MARKERS
Lymph node
Aged
80 and over
medicine.diagnostic_test
Middle Aged
lymph node
CANCER
Fine-needle aspiration
medicine.anatomical_structure
Cervical lymph nodes
Head and Neck Neoplasms
030220 oncology & carcinogenesis
Lymphatic Metastasis
Carcinoma
Squamous Cell
Female
Original Article
Lymph
Adult
medicine.medical_specialty
Adolescent
Biopsy
Fine-Needle
SCC‐Ag
Sensitivity and Specificity
03 medical and health sciences
Young Adult
Antigens
Neoplasm
medicine
Humans
neoplasms
Tumor marker
Aged
Retrospective Studies
SCC-Ag
business.industry
Cancer
Original Articles
medicine.disease
Head and neck squamous-cell carcinoma
stomatognathic diseases
SIZE
Otorhinolaryngology
FNA
tumor marker
030221 ophthalmology & optometry
Lymph Nodes
business
Zdroj: Head and Neck: Journal of the Sciences and Specialties of the Head and Neck, 41(8), 2561-2565. Wiley
Head & Neck
ISSN: 1097-0347
1043-3074
Popis: BACKGROUND: The purpose of this study was to determine the additional diagnostic value of squamous cell carcinoma antigen (SCC-Ag) in cervical lymph node fine needle aspiration (FNA) samples for the detection of regional metastases of head and neck squamous cell carcinoma (HNSCC).METHODS: In 149 FNA samples of 114 patients, SCC-Ag concentration was retrospectively analyzed and associated with diagnosis to establish a cutoff concentration in relation to sensitivity and specificity of HNSCC detection.RESULTS: SCC-Ag was elevated in lymph nodes from patients with HNSCC compared to lymph nodes from other patients (P CONCLUSIONS: SCC-Ag in FNA is a reliable test for detecting HNSCC in cervical lymph nodes.
Databáze: OpenAIRE
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