New types of synthetic infusion solutions. III. Elimination and retention of poly-[N-(2-hydroxypropyl)methacrylamide] in a test organism
| Autor: | Jindřich Kopeček, L. Sprincl, Stĕrba O, J. Exner |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
chemistry.chemical_classification
Molecular mass Acrylic Resins Plasma Substitutes Biomedical Engineering Polymer Molecular Weight Biomaterials chemistry.chemical_compound Polymethacrylic Acids chemistry Animals Methacrylamide Organic chemistry Test organism Rabbits N-(2-Hydroxypropyl) methacrylamide |
| Zdroj: | Journal of Biomedical Materials Research. 10:953-963 |
| ISSN: | 1097-4636 0021-9304 |
| DOI: | 10.1002/jbm.820100612 |
| Popis: | The elimination and retention of a new, fully synthetic plasma prosthesis of Czechoslovak origin under the working name of Duxon (poly[N-(2-hydroxypropyl)methacrylamide]) was investigated in experiments on rabbits by using a 14C-labeled polymer. Results published earlier on elimination have been confirmed and extended. Retention was examined after repeated application. The effect of molecular weight prevailed both in elimination and in retention. Polymers of lower molecular weights, which possess a good therapeutical effect, are not permanently deposited in the organism. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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