International Multicenter Experience of Isolated Limb Infusion for In-Transit Melanoma Metastases in Octogenarian and Nonagenarian Patients

Autor:	B. Mark Smithers, Brendon J. Coventry, Jeffrey M. Farma, Michael C. Lowe, Andrew Barbour, Clara R. Farley, Jonathan S. Zager, Douglas S. Tyler, James Sun, David Speakman, Jonathan W. Serpell, Paul J. Mosca, Michael J Carr, Tim Kenyon-Smith, Keith A. Delman, John F. Thompson, Norma E. Farrow, Dean Mullen, Michael A. Henderson, Jueni Teras, John T. Miura, Georgia M. Beasley, Hidde M. Kroon, Aishwarya Potdar, Hala Daou
Rok vydání:	2020
Předmět:	Male Melphalan medicine.medical_specialty Neoplasm Residual Skin Neoplasms medicine.medical_treatment Upper Extremity 03 medical and health sciences 0302 clinical medicine Surgical oncology Internal medicine Antineoplastic Combined Chemotherapy Protocols medicine Humans Progression-free survival Neoplasm Metastasis Melanoma Neoplasm Staging Aged 80 and over Chemotherapy business.industry Australia Cancer Length of Stay medicine.disease Progression-Free Survival United States Tumor Burden Treatment Outcome medicine.anatomical_structure Lower Extremity Oncology Chemotherapy Cancer Regional Perfusion 030220 oncology & carcinogenesis Cohort Dactinomycin Upper limb Female 030211 gastroenterology & hepatology Surgery business medicine.drug
Zdroj:	Annals of Surgical Oncology. 27:1420-1429
ISSN:	1534-4681 1068-9265
DOI:	10.1245/s10434-020-08312-0
Popis:	Isolated limb infusion (ILI) is used to treat in-transit melanoma metastases confined to an extremity. However, little is known about its safety and efficacy in octogenarians and nonagenarians (ON). ON patients (≥ 80 years) who underwent a first ILI for American Joint Committee on Cancer seventh edition stage IIIB/IIIC melanoma between 1992 and 2018 at nine international centers were included and compared with younger patients (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e20afd447b64e94371ef7247c000ea71 https://doi.org/10.1245/s10434-020-08312-0 Zobrazit plný text záznamu Full text from SpringerLink