An image fusion system for estimating the therapeutic effects of radiofrequency ablation on hepatocellular carcinoma
| Autor: | Mikihiro Tsutsumi, Nobuyuki Toshikuni, Yasuhiro Matsue, Nobuhiko Hayashi, Kazuaki Ozaki, Mutsumi Tsuchishima, Kaho Yamada |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Radiofrequency ablation medicine.medical_treatment R895-920 image fusion 030218 nuclear medicine & medical imaging law.invention Medical physics. Medical radiology. Nuclear medicine 03 medical and health sciences 0302 clinical medicine law Medicine Radiology Nuclear Medicine and imaging Image fusion business.industry Therapeutic effect Ultrasound hepatocellular carcinoma Ablation medicine.disease Surgery surgical procedures operative Patient burden Oncology Hepatocellular carcinoma Microbubbles 030211 gastroenterology & hepatology radiofrequency ablation business Nuclear medicine therapeutics Research Article |
| Zdroj: | Radiology and Oncology Radiology and Oncology, Vol 51, Iss 3, Pp 263-269 (2017) |
| ISSN: | 1581-3207 |
| DOI: | 10.1515/raon-2017-0028 |
| Popis: | BackgroundDuring ultrasound-guided radiofrequency ablation (RFA) of hepatocellular carcinoma (HCC), high echoic areas due to RFA-induced microbubbles can help calculate the extent of ablation. However, these areas also decrease visualization of target tumors, making it difficult to assess whether they completely cover the tumors. To estimate the effects of RFA more precisely, we used an image fusion system (IFS).Patients and methodsWe enrolled patients with a single HCC who received RFA with or without the IFS. In the IFS group, we drew a spherical marker along the contour of a target tumor on reference images immediately after administering RFA so that the synchronized spherical marker represented the contour of the target tumor on real-time ultrasound images. When the high echoic area completely covered the marker, we considered the ablation to be complete. We compared outcomes between the IFS and control groups.ResultsWe enrolled 25 patients and 20 controls, and the baseline characteristics were similar between the two groups. The complete ablation rates during the first RFA session were significantly higher in the IFS group compared with those in the control group (88.0%vs. 60.0%,P= 0.041). The number of RFA sessions was significantly smaller in the IFS group compared with that in the control group (1.1 ± 0.3vs. 1.5 ± 0.7,P= 0.016).ConclusionsThe study suggested that the IFS enables a more precise estimation of the effects of RFA on HCC, contributing to enhanced treatment efficacy and minimized patient burden. |
| Databáze: | OpenAIRE |
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