Pattern of myelin proteins in moderate hypoxia
| Autor: | Wender M, D. Talkowska, Z. Adamczewska-Goncerzewicz, A. Grochowalska, Pankrac J |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
medicine.medical_specialty
Molecular mass chemistry.chemical_element Rats Inbred Strains Hypoxia (medical) Biology Oxygen Rats Pathology and Forensic Medicine Myelin Endocrinology medicine.anatomical_structure Biochemistry chemistry Inbred strain Internal medicine Respiration medicine Major basic protein biology.protein Animals Moderate hypoxia medicine.symptom Hypoxia Myelin Proteins |
| Zdroj: | Experimental Pathology. 39:45-48 |
| ISSN: | 0232-1513 |
| Popis: | Myelin proteins isolated from the brain of Wistar rats subjected to moderate hypoxia (7% of oxygen in a respiration gaseous mixture) for 30 min were investigated. Among the various protein fractions Wolfgram protein happened to be most markedly affected, demonstrating considerably lowered percentages in all experimental groups, starting from 24 h after hypoxia. Our findings compared with those obtained in other experimental conditions lead to the conclusion that changes in the myelin protein pattern are characteristic for particular morbid processes evoked by various pathogenic factors. The demyelination is concomitant with severe loss of basic proteins, whereas myelin lesions of other types are connected with changes in protein of higher molecular mass. |
| Databáze: | OpenAIRE |
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