Effects of intraperitoneal injection of lipopolysaccharide-induced peripheral inflammation on dopamine neuron damage in rat midbrain

Autor:	Qiu‐Yu Yang, Xian‐Wei Li, Rong Yang, Ting‐Yang Qin, Hong Long, Shi‐Bin Zhang, Feng Zhang
Rok vydání:	2022
Předmět:	Pharmacology Inflammation Lipopolysaccharides Dopaminergic Neurons Rats Substantia Nigra Psychiatry and Mental health Mesencephalon Physiology (medical) Animals Pharmacology (medical) Microglia RNA Messenger Biomarkers Injections Intraperitoneal
Zdroj:	CNS neurosciencetherapeutics. 28(10)
ISSN:	1755-5949
Popis:	Current studies have documented neuroinflammation is implicated in Parkinson's disease. Recently, growing evidence indicated peripheral inflammation plays an important role in regulation of neuroinflammation and thus conferring protection against dopamine (DA) neuronal damage. However, the underlying mechanisms are not clearly illuminated.The effects of intraperitoneal injection of LPS (LPSLPSThis study suggested LPS
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f61cdf7d4f6c014cd128afde0dc819 https://pubmed.ncbi.nlm.nih.gov/35789066 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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