Antenatal suspicion of ischemic placental disease and coexistence of maternal and fetal placental disease: analysis of over 500 cases
| Autor: | Eoghan E. Mooney, Sharon Cooley, Fiona R. Reidy, Fionnuala M. McAuliffe |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
medicine.medical_specialty Placenta Diseases Prenatal diagnosis Chorioamnionitis Young Adult Ischemia Pregnancy Risk Factors Prenatal Diagnosis medicine Humans Placental Circulation Prospective Studies Prospective cohort study Gynecology Obstetrics business.industry Vascular disease Incidence Pregnancy Outcome Obstetrics and Gynecology Thrombosis medicine.disease Placental disease Fetal Diseases Premature birth Premature Birth Female Morbidity business |
| Zdroj: | American journal of obstetrics and gynecology. 205(6) |
| ISSN: | 1097-6868 |
| Popis: | Objective To investigate the antenatal suspicion of placental disease and the coexistence of maternal and fetal placental ischemic disease. Study Design A prospective cohort study on normally formed singleton infants from 2000 to 2008 inclusive with placental ischemic disease. Results Uteroplacental ischemia or fetoplacental thrombotic vasculopathy was identified in 511 of 74,857 births (7/1000 births). Four hundred fifty-nine cases met the inclusion criteria. Maternal and fetal placental vascular disease coexisted in 9.2% (n = 42) of cases. Placental ischemic disease was suspected antenatally in 70% (324/459). Maternal placental disease occurred in 40% (184/459) and 30% (140/459) had fetal pathology. The perinatal mortality rate was 12.7/1000. Antenatal suspicion of placental disease led to increased obstetric intervention and delivery of small-for-gestational age infants. Conclusion Maternal and fetoplacental vascular disease coexisted in 9.2%. Placental disease was suspected antenatally in 70% of cases and was associated with increased rates of obstetric intervention. |
| Databáze: | OpenAIRE |
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