Localization of the gene for human heart fatty acid binding protein to chromosome 1p32-1p33
| Autor: | Herman E. Wyandt, James Skare, Jen-Wei Jiang, Gwynneth D. Offner, Aubrey Milunsky, Bai-Lin Wu, Robert F. Troxler |
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| Rok vydání: | 1993 |
| Předmět: |
Molecular Sequence Data
Biology Fatty Acid-Binding Proteins Polymerase Chain Reaction Fatty acid-binding protein Complementary DNA Genetics medicine Humans Amino Acid Sequence Metaphase In Situ Hybridization Fluorescence Genetics (clinical) Base Sequence medicine.diagnostic_test Myocardium Tumor Suppressor Proteins Endoplasmic reticulum Binding protein Fatty Acids Chromosome Mapping DNA Peroxisome Molecular biology Neoplasm Proteins Biochemistry Chromosomes Human Pair 1 Heart-type fatty acid binding protein Carrier Proteins DNA Probes Fatty Acid-Binding Protein 7 Fluorescence in situ hybridization |
| Zdroj: | Human Genetics. 92:563-566 |
| ISSN: | 1432-1203 0340-6717 |
| DOI: | 10.1007/bf00420939 |
| Popis: | Heart fatty acid binding protein (hFABP) is an abundant 14-kDa cytosolic protein thought to be involved in trafficking of fatty acids from the plasma membrane to sites of beta-oxidation in mitochondria and peroxisomes and to the endoplasmic reticulum for lipid synthesis. A human hFABP cDNA isolated by polymerase chain reaction was used as a probe for in situ hybridization to metaphase chromosomes. A fragment of the gene for human hFABP was used as a probe for fluorescence in situ hybridization to metaphase chromosomes. The cDNA and genomic probes both localized the gene for human hFABP to chromosome 1p32-1p33. |
| Databáze: | OpenAIRE |
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