The emergence and outbreak of multidrug-resistant typhoid fever in China
| Autor: | Mei-Ying Yan, Qiaohong Liao, Biao Kan, Xinlan Li, Jing Zhang, Fang Li |
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| Rok vydání: | 2016 |
| Předmět: |
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Bacterial 0301 basic medicine China medicine.medical_specialty Genotype Epidemiology 030106 microbiology Immunology Biology Salmonella typhi complex mixtures Microbiology Typhoid fever Disease Outbreaks 03 medical and health sciences multidrug resistance Drug Resistance Multiple Bacterial Virology Environmental health Drug Discovery medicine Humans Typhoid Fever outbreak Public health Outbreak General Medicine bacterial infections and mycoses medicine.disease Intestinal infectious diseases Anti-Bacterial Agents Multiple drug resistance Infectious Diseases Original Article Parasitology Plasmids |
| Zdroj: | Emerging Microbes & Infections |
| ISSN: | 2222-1751 |
| DOI: | 10.1038/emi.2016.62 |
| Popis: | Typhoid fever remains a severe public health problem in developing countries. The emergence of resistant typhoid, particularly multidrug-resistant typhoid infections, highlights the necessity of monitoring the resistance characteristics of this invasive pathogen. In this study, we report a typhoid fever outbreak caused by multidrug-resistant Salmonella enterica serovar Typhi strains with an ACSSxtT pattern. Resistance genes conferring these phenotypes were harbored by a large conjugative plasmid, which increases the threat of Salmonella Typhi and thus requires close surveillance for dissemination of strains containing such genes. |
| Databáze: | OpenAIRE |
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