Optimising daytime deliveries when inducing labour using prostaglandin vaginal inserts

Autor: Laura Goetzl, Olof Rugarn, Hugh Miller, Deborah A. Wing, Barbara Powers
Rok vydání: 2016
Předmět:
medicine.medical_specialty
Time Factors
induction of labour
Prostaglandin
Inducing labour
Active labour
Article
Dinoprostone
Drug Administration Schedule
Paediatrics and Reproductive Medicine
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Double-Blind Method
Pregnancy
Secondary analysis
Oxytocics
Medicine
Humans
Start time
030212 general & internal medicine
Labor
Induced

Obstetrics & Reproductive Medicine
Misoprostol
Vaginal insert
Gynecology
misoprostol
030219 obstetrics & reproductive medicine
business.industry
Suppositories
Induced
Obstetrics and Gynecology
Obstetric
Delivery
Obstetric

Labor
Parity
chemistry
Daytime deliveries
retrievable prostaglandin vaginal delivery systems
Median time
Pediatrics
Perinatology and Child Health

Original Article
Female
business
Delivery
medicine.drug
Zdroj: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, vol 29, iss 4
Miller, H; Goetzl, L; Wing, DA; Powers, B; & Rugarn, O. (2016). Optimising daytime deliveries when inducing labour using prostaglandin vaginal inserts. Journal of Maternal-Fetal and Neonatal Medicine, 29(4), 517-522. doi: 10.3109/14767058.2015.1011117. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/3k2585tn
The Journal of Maternal-Fetal & Neonatal Medicine
Popis: © 2015 The Author(s). Published by Taylor & Francis. Objective: To determine induction start time(s) that would maximise daytime deliveries when using prostaglandin vaginal inserts.Methods: Women enrolled into the Phase III trial, EXPEDITE (clinical trial registration: NCT01127581), had labour induced with either a misoprostol or dinoprostone vaginal insert (MVI or DVI). A secondary analysis was conducted to determine the optimal start times for induction by identifying the 12-h period with the highest proportion of deliveries by parity and treatment.Results: Optimal start times for achieving daytime deliveries when using MVI appear to be 19:00 in nulliparae and 23:00 in multiparae. Applying these start times, the median time of onset of active labour would be approximately 08:30 for both parities and the median time of delivery would be the following day at approximately 16:30 for nulliparae and 12:00 (midday) for multiparae. Optimal start times when using DVI appear to be 07:00 for nulliparae and 23:00 for multiparae. Using these start times, the median time of onset of active labour would be the following day at approximately 04:00 and 11:50, and the median time of delivery would be approximately 13:40 and 16:10, respectively.Conclusions: When optimising daytime deliveries, different times to initiate induction of labour may be appropriate depending on parity and the type of retrievable prostaglandin vaginal insert used.
Databáze: OpenAIRE