Influence of pemphigoid gestationis on pregnancy outcome: A case report and review of the literature
| Autor: | Roxana Elena Bohiltea, Corina Grigoriu, Dimitrie Pelinescu‑Onciul, Caliopia Gavril Parfene, Corina-Aurelia Zugravu, Irina Margaritescu, Aurel Doru Chirita, Bianca Margareta Mihai |
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| Rok vydání: | 2021 |
| Předmět: |
Cancer Research
medicine.medical_specialty Pregnancy integumentary system medicine.diagnostic_test business.industry Obstetrics Standard treatment Intrauterine growth restriction Articles General Medicine medicine.disease Immunology and Microbiology (miscellaneous) Pemphigoid Gestationis Skin biopsy Fetal distress Medicine Differential diagnosis skin and connective tissue diseases business Dermatoses of pregnancy |
| Zdroj: | Exp Ther Med |
| ISSN: | 1792-1015 1792-0981 |
| Popis: | Pemphigoid gestationis is considered to be a rare pregnancy exclusive bullous disease, which modifies the course of the pregnancy, with difficulties in the management of the pruritus and skin lesions as well as a possible change in the neonatal outcome. Differential diagnosis of skin lesions and pruritus in pregnancy is challenging, and complementary investigations such as skin biopsy or laboratory tests are indispensable. The correct diagnosis and proper treatment could change the natural course of a pregnancy at risk and could improve maternal and fetal morbidity. We present the case of a patient with pemfigoid gestationis with the aim to highlight: i) the management of this pregnancy-associated skin disorder which transfers this pregnancy into a category of high obstetrical risk pregnancy; ii) the particularities of the course of the pregnancy; and iii) the importance in the differential diagnosis of pregnancy dermatoses. The particularity of this case of pemphigoid gestationis was the acute fetal distress in the absence of intrauterine growth restriction that is frequently found in this pathology, and the management of a rare pregnancy skin condition that currently has no standard treatment. |
| Databáze: | OpenAIRE |
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