SARS‐CoV‐2 rapid antigen test in comparison to RT‐PCR targeting different genes: A real‐life evaluation among unselected patients in a regional hospital of Italy
| Autor: | Barbara Pajola, Carlo Lorenzi, Valentina Serafini, Donatella Piccoli, Andrea Ragusa, Antonio Conti, Manuela Mistretta, Sara Caldrer, Francesca Perandin, Marco Boni, Pierantonio Orza, Chiara Piubelli, Davide Treggiari |
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| Rok vydání: | 2021 |
| Předmět: |
Panbio™ COVID‐19
medicine.medical_specialty RT‐PCR Short Communication Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Population Short Communications Context (language use) Sensitivity and Specificity Gastroenterology SARS‐CoV‐2 Antigen Virology Internal medicine Humans Medicine Serologic Tests education Antigens Viral Gene education.field_of_study Reverse Transcriptase Polymerase Chain Reaction SARS-CoV-2 business.industry RAD COVID-19 Hospitals Infectious Diseases Real-time polymerase chain reaction Rapid antigen test business Viral load |
| Zdroj: | Journal of Medical Virology |
| ISSN: | 1096-9071 0146-6615 |
| DOI: | 10.1002/jmv.27378 |
| Popis: | We assessed the performance of the Panbio rapid antigen detection (RAD) test for the detection of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and we compared it with the routine reverse transcriptase‐polymerase chain reaction (RT‐PCR)‐based molecular test in a population of 4167 unselected patients admitted to IRCCS Sacro Cuore Don Calabria Hospital. Analysis stratified by cycling threshold (C t) value of SARS‐CoV‐2 gene targets indicated that antigen (Ag)‐positive C t values were significantly lower compared to Ag‐negative values (p |
| Databáze: | OpenAIRE |
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