Maternal early-pregnancy vitamin D status is associated with maternal depressive symptoms in the Amsterdam Born Children and Their Development cohort

Autor: Joke Brandenbarg, Manon van Eijsden, Geertje Goedhart, Tanja G. M. Vrijkotte
Přispěvatelé: APH - Amsterdam Public Health, ARD - Amsterdam Reproduction and Development, Public and occupational health
Rok vydání: 2012
Předmět:
Zdroj: Psychosomatic medicine, 74(7), 751-757. Lippincott Williams and Wilkins
ISSN: 1534-7796
0033-3174
Popis: Objective: To examine low maternal vitamin D status as a potential risk factor for high levels of depressive symptoms in a pregnant population. Methods: In the Amsterdam Born Children and Their Development cohort, maternal serum vitamin D (n = 4236) was measured during early pregnancy (median, 13 weeks) and labeled "deficient" ( = 80 nM). Maternal depressive symptoms were measured by the Center for Epidemiological Studies Depression Scale at 16-week gestation. The association of vitamin D status with high levels of depressive symptoms (Center for Epidemiological Studies Depression score >= 16) was assessed by multivariate logistic regression (final sample, 4101). Results: Overall, 23% of women had vitamin D deficiency, and 21% of women had vitamin D insufficiency. Women with high levels of depressive symptoms (28%) had lower vitamin D concentrations than women with low levels of depressive symptoms (p
Databáze: OpenAIRE