A nomogram for the prediction of renal outcomes among patients with idiopathic membranous nephropathy
| Autor: | Duo Li, Zhanyuan Li, Min Pan, Shufang Pan, Lingwei Jin, Zhihong Zhou, Ji Zhang |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Cancer Research
medicine.medical_specialty Proteinuria medicine.diagnostic_test Proportional hazards model business.industry renal outcomes Hazard ratio Urology idiopathic membranous nephropathy Cancer Renal function Retrospective cohort study Articles General Medicine Nomogram urologic and male genital diseases medicine.disease Immunology and Microbiology (miscellaneous) medicine prognostic model Renal biopsy medicine.symptom business chronic kidney disease |
| Zdroj: | Experimental and Therapeutic Medicine |
| ISSN: | 1792-1015 1792-0981 |
| DOI: | 10.3892/etm.2020.9063 |
| Popis: | The early prediction of renal outcomes in patients with idiopathic membranous nephropathy (iMN) remains challenging. The present retrospective study evaluated patients with iMN confirmed by renal biopsy. An optimized Cox regression model and a nomogram were constructed for the early prediction of renal outcomes. A total of 141 patients who met the inclusion criteria were evaluated in the present study. In total 18 (12.8%) patients eventually progressed to the endpoint, 6 of whom developed end-stage renal disease, and one patient died during follow-up. The optimized model demonstrated that 24-h proteinuria [hazard ratio (HR) 1.24; 95% CI, 1.10-1.40; P-value |
| Databáze: | OpenAIRE |
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