Malignant Otitis Externa: Causes for Various Treatment Responses
| Autor: | Zoran Dudvarski, Snezana Jesic, Snezana Babac, Ljiljana Cvorovic, Nenad Arsovic, Nemanja Radivojevic |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Facial Paralysis Comorbidity Disease Malignant otitis externa Necrosis 03 medical and health sciences 0302 clinical medicine Recurrence Diabetes mellitus Internal medicine Temporal bone Diabetes Mellitus Humans Medicine Pseudomonas Infections In patient Ear External 030223 otorhinolaryngology Aged Retrospective Studies Aged 80 and over business.industry Temporal Bone General Medicine Middle Aged lcsh:Otorhinolaryngology Otitis Externa Prognosis medicine.disease lcsh:RF1-547 Anti-Bacterial Agents Otitis Otorhinolaryngology 030220 oncology & carcinogenesis Pseudomonas aeruginosa Facial nerve palsy Original Article Female medicine.symptom Tomography X-Ray Computed business |
| Zdroj: | J Int Adv Otol Journal of International Advanced Otology, Vol 16, Iss 1, Pp 98-103 (2020) |
| ISSN: | 2148-3817 1308-7649 |
| DOI: | 10.5152/iao.2020.7709 |
| Popis: | OBJECTIVES: Malignant (necrotizing) otitis externa (MOE) is an aggressive form of skin inflammation of the external ear with a tendency to spread infection to the temporal bone. The study aimed to evaluate a causal relationship between treatment responses and clinical features in patients with MOE. MATERIALS AND METHODS: In a retrospective, descriptive section study, the database was analyzed between January 2008 and December 2018 in our department, all patients with diagnosed MOE were identified. RESULTS: A total of 30 patients were evaluated, of which 27 men and 3 women. The youngest patient was 52 years old while he was eldest 88 years, (mean-71 years old). As the most common comorbidity, diabetes mellitus was found in 23 (76%) subjects. Median duration of symptoms was about 3 months. The most common isolated pathogen was Pseudomonas aeruginosa (47%). Patients with facial nerve palsy and erosion of temporal bone find on computerized tomography affect prolonged stationary treatment (Mean, SD 29.2±8.5 and 26,7±11.6 days), while 80% of patients with facial nerve palsy had recurrence of disease (p=0.005) with mean duration of clinical remission of 60±17.3 days. Overall length of treatment is also increased in the presence of comorbidities as well as in patients with cranial nerve involvement. CONCLUSION: Patients with cranial nerve involvement, erosion of temporal bone and presence of comorbidities affect prolonged treatment and adverse prognosis. Early diagnosis and initiation of aggressive therapy are essential for stopping the further spread of the disease and prevention of serious complications. |
| Databáze: | OpenAIRE |
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