Choroidal thickness maps from spectral domain and swept source optical coherence tomography: algorithmic versus ground truth annotation
| Autor: | Ursula Schmidt-Erfurth, Hrvoje Bogunovic, Sebastian M. Waldstein, Henrik Faatz, Dominika Podkowinski, Ana-Maria Philip, Roland Leitner, Li Zhang, Michael Hagmann, Michael D. Abràmoff, Bianca S. Gerendas, Milan Sonka, Christian Simader |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Systematic difference genetic structures Automated segmentation Spectral domain Article Young Adult 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Optical coherence tomography Healthy volunteers Humans Medicine medicine.diagnostic_test Choroid business.industry Reproducibility of Results Grid cell Healthy Volunteers eye diseases Sensory Systems Ophthalmology Cross-Sectional Studies medicine.anatomical_structure 030221 ophthalmology & optometry Female sense organs Ground truth annotation business Algorithms Tomography Optical Coherence 030217 neurology & neurosurgery Biomedical engineering |
| Zdroj: | British Journal of Ophthalmology. 100:1372-1376 |
| ISSN: | 1468-2079 0007-1161 |
| DOI: | 10.1136/bjophthalmol-2015-307985 |
| Popis: | The purpose of the study was to create a standardised protocol for choroidal thickness measurements and to determine whether choroidal thickness measurements made on images obtained by spectral domain optical coherence tomography (SD-OCT) and swept source (SS-) OCT from patients with healthy retina are interchangeable when performed manually or with an automatic algorithm.36 grid cell measurements for choroidal thickness for each volumetric scan were obtained, which were measured for SD-OCT and SS-OCT with two methods on 18 eyes of healthy volunteers. Manual segmentation by experienced retinal graders from the Vienna Reading Center and automated segmentation on6300 images of the choroid from both devices were statistically compared.Model-based comparison between SD-OCT/SS-OCT showed a systematic difference in choroidal thickness of 16.26±0.725 μm (p0.001) for manual segmentation and 21.55±0.725 μm (p0.001) for automated segmentation. Comparison of automated with manual segmentations revealed small differences in thickness of -0.68±0.513 μm (p=0.1833). The correlation coefficients for SD-OCT and SS-OCT measures within eyes were 0.975 for manual segmentation and 0.955 for automatic segmentation.Choroidal thickness measurements of SD-OCT and SS-OCT indicate that these two devices are interchangeable with a trend of choroidal thickness measurements being slightly thicker on SD-OCT with limited clinical relevance. Use of an automated algorithm to segment choroidal thickness was validated in healthy volunteers. |
| Databáze: | OpenAIRE |
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