Psoriasis: Embarking a dynamic shift in the skin microbiota
Autor: | Paul S. Yamauchi, Stephan Grabbe, Mrinal Gupta, Jeffrey M Weinberg, Anant Patil, Mohamad Goldust |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Exacerbation 610 Medizin MEDLINE Skin flora Dermatology 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine 610 Medical sciences Psoriasis Candida albicans medicine Animals Humans Microbiome Skin Malassezia biology business.industry Microbiota biology.organism_classification medicine.disease Clinical trial 030220 oncology & carcinogenesis business |
Zdroj: | Journal of Cosmetic Dermatology. 21:1402-1406 |
ISSN: | 1473-2165 1473-2130 |
Popis: | Recent interest has arisen regarding the role of microbiome and its composition in the pathogenesis of psoriasis. Numerous studies have shown that there are alterations in skin flora arrangement between normal individuals and psoriatic patients. Psoriasis exacerbation could be interconnected with epidermal or mucosal colonization with streptococci, Malassezia, Staphylococcus aureus, or Candida albicans. The role of cutaneous and gut microbiome in psoriasis pathogenesis has recently been studied in both human and animal models. In this review, we try to evaluate various pathogenic mechanisms linking the microbiota and psoriasis. The literature research included peer-reviewed articles which included clinical trials, original reports, and scientific reviews. MEDLINE and PubMed databases were searched from January 1990 to March 2021, including the reference lists of articles meeting our criteria. |
Databáze: | OpenAIRE |
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