Development of a Neurodegenerative Disease Gait Classification Algorithm Using Multiscale Sample Entropy and Machine Learning Classifiers
| Autor: | Che-Wei Lin, An Bang Liu, Quoc Duy Nam Nguyen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Computer science
Feature extraction General Physics and Astronomy lcsh:Astrophysics 02 engineering and technology Machine learning computer.software_genre Neurodegenerative disease Article 03 medical and health sciences 0302 clinical medicine Gait (human) Time windows lcsh:QB460-466 0202 electrical engineering electronic engineering information engineering Preprocessor Oversampling lcsh:Science business.industry multiscale sample entropy lcsh:QC1-999 Sample entropy Support vector machine Gait analysis gait analysis 020201 artificial intelligence & image processing lcsh:Q Artificial intelligence business computer Algorithm 030217 neurology & neurosurgery lcsh:Physics |
| Zdroj: | Entropy, Vol 22, Iss 1340, p 1340 (2020) Entropy Volume 22 Issue 12 |
| ISSN: | 1099-4300 |
| Popis: | The prevalence of neurodegenerative diseases (NDD) has grown rapidly in recent years and NDD screening receives much attention. NDD could cause gait abnormalities so that to screen NDD using gait signal is feasible. The research aim of this study is to develop an NDD classification algorithm via gait force (GF) using multiscale sample entropy (MSE) and machine learning models. The Physionet NDD gait database is utilized to validate the proposed algorithm. In the preprocessing stage of the proposed algorithm, new signals were generated by taking one and two times of differential on GF and are divided into various time windows (10/20/30/60-sec). In feature extraction, the GF signal is used to calculate statistical and MSE values. Owing to the imbalanced nature of the Physionet NDD gait database, the synthetic minority oversampling technique (SMOTE) was used to rebalance data of each class. Support vector machine (SVM) and k-nearest neighbors (KNN) were used as the classifiers. The best classification accuracies for the healthy controls (HC) vs. Parkinson&rsquo s disease (PD), HC vs. Huntington&rsquo s disease (HD), HC vs. amyotrophic lateral sclerosis (ALS), PD vs. HD, PD vs. ALS, HD vs. ALS, HC vs. PD vs. HD vs. ALS, were 99.90%, 99.80%, 100%, 99.75%, 99.90%, 99.55%, and 99.68% under 10-sec time window with KNN. This study successfully developed an NDD gait classification based on MSE and machine learning classifiers. |
| Databáze: | OpenAIRE |
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