Well-differentiated gall bladder hepatoid carcinoma producing alpha-fetoprotein: a case report
| Autor: | Ching-Yun Kao, Hung Chiang, Che-Yu Cheng, Chian-Ro Chang, Ma Shih-Ming, How-Tshung Chen |
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| Rok vydání: | 2009 |
| Předmět: |
Medicine(all)
medicine.medical_specialty Pathology business.industry lcsh:R digestive oral and skin physiology lcsh:Medicine General Medicine urologic and male genital diseases medicine.disease digestive system Gastroenterology digestive system diseases Well differentiated Hepatoid Carcinoma fluids and secretions Surgical oncology Internal medicine Hepatocellular carcinoma Case report Medicine Gall Gall bladder carcinoma business Alpha-fetoprotein |
| Zdroj: | Journal of Medical Case Reports Journal of Medical Case Reports, Vol 3, Iss 1, p 7303 (2009) |
| ISSN: | 1752-1947 |
| DOI: | 10.4076/1752-1947-3-7303 |
| Popis: | Introduction Gall bladder carcinoma is rare, and metastatic gall bladder carcinoma from hepatocellular carcinoma has been reported in only a few patients. Case presentation We present a 73-year-old man with a history of hepatitis B virus-related liver cirrhosis and hepatocellular carcinoma. He received transcatheter arterial chemoembolization, and was diagnosed to have an alpha-fetoprotein producing gall bladder tumor with intraluminal growth. Open cholecystectomy was performed. Pathologic examination of the lesion revealed a well-differentiated hepatoid carcinoma. The lesion was thought most likely to be a metastatic lesion from previous hepatocellular carcinoma. His alpha-fetoprotein level dropped to normal levels five months after the surgery. Conclusion This unusual intraluminal growing tumor proved to be a well-differentiated hepatoid carcinoma, most likely a metastatic lesion from previous hepatocellular carcinoma. This case reminds clinicians that in looking for likely hepatocellular carcinoma recurrence, when no detectable hepatic lesion can account for an elevated alpha-fetoprotein level, the gall bladder should be included in the search for the site of metastasis. |
| Databáze: | OpenAIRE |
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