The brain’s structural differences between postherpetic neuralgia and lower back pain
| Autor: | Rushi Zou, Bing Wu, Xiaowei Sun, Linling Li, Jing Liu, Zhiguo Zhang, Zengmao Lin, Juan Wei, Jianxing Qiu, Mengjiao Du, Naishan Qin, Junzhe Yang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Science Inferior frontal gyrus Neuralgia Postherpetic Grey matter urologic and male genital diseases Neural circuits Article Gyrus Internal medicine Back pain medicine Connectome Middle frontal gyrus Humans Prospective Studies Gray Matter Aged Cerebral Cortex Multidisciplinary Fusiform gyrus Postherpetic neuralgia business.industry Incidence Middle Aged medicine.disease Magnetic Resonance Imaging nervous system diseases medicine.anatomical_structure Cardiology Neuronal physiology Medicine Female medicine.symptom business Insula Low Back Pain |
| Zdroj: | Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021) Scientific Reports |
| ISSN: | 2045-2322 |
| Popis: | The purpose is to explore the brain’s structural difference in local morphology and between-region networks between two types of peripheral neuropathic pain (PNP): postherpetic neuralgia (PHN) and lower back pain (LBP). A total of 54 participants including 38 LBP and 16 PHN patients were enrolled. The average pain scores were 7.6 and 7.5 for LBP and PHN. High-resolution structural T1 weighted images were obtained. Both grey matter volume (GMV) and morphological connectivity (MC) were extracted. An independent two-sample t-test with false discovery rate (FDR) correction was used to identify the brain regions where LBP and PHN patients showed significant GMV difference. Next, we explored the differences of MC network between LBP and PHN patients and detected the group differences in network properties by using the two-sample t-test and FDR correction. Compared with PHN, LBP patients had significantly larger GMV in temporal gyrus, insula and fusiform gyrus (p p p p |
| Databáze: | OpenAIRE |
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