The nocturnal leopard gecko (Eublepharis macularius) uses UVb radiation for vitamin D3 synthesis
| Autor: | Oonincx, D G A B, Diehl, J J E, Kik, M, Baines, F M, Heijboer, A C, Hendriks, W H, Bosch, G, VPDC pathologie, dPB I&I, dPB CR, FAH voeding, LS Heelkunde |
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| Přispěvatelé: | VPDC pathologie, dPB I&I, dPB CR, FAH voeding, LS Heelkunde, Endocrinology Laboratory, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, AMS - Musculoskeletal Health, Laboratory Medicine, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam Reproduction & Development (AR&D) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Vitamin
medicine.medical_specialty Animal Nutrition Bone density 040301 veterinary sciences Physiology Reptile Eublepharis de novo synthesis Biochemistry vitamin D deficiency 0403 veterinary science 03 medical and health sciences chemistry.chemical_compound Internal medicine Ultraviolet light medicine Vitamin D and neurology Molecular Biology 030304 developmental biology 0303 health sciences biology 04 agricultural and veterinary sciences biology.organism_classification medicine.disease Diervoeding Night active Endocrinology chemistry Feed WIAS Leopard gecko medicine.symptom Weight gain Ultraviolet lightde novo synthesis |
| Zdroj: | Comparative Biochemistry and Physiology Part-B: Biochemistry and Molecular Biology 250 (2020) Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 250:110506. Elsevier Inc. Oonincx, D G A B, Diehl, J J E, Kik, M, Baines, F M, Heijboer, A C, Hendriks, W H & Bosch, G 2020, ' The nocturnal leopard gecko (Eublepharis macularius) uses UVb radiation for vitamin D 3 synthesis ', Comparative Biochemistry and Physiology Part-B: Biochemistry and Molecular Biology, vol. 250, 110506 . https://doi.org/10.1016/j.cbpb.2020.110506 Comparative biochemistry and physiology. B, Comparative biochemistry, 250. Elsevier Comparative Biochemistry and Physiology Part-B: Biochemistry and Molecular Biology, 250:110506. Elsevier Inc. Comparative Biochemistry and Physiology Part-B: Biochemistry and Molecular Biology, 250 |
| ISSN: | 1096-4959 |
| DOI: | 10.1016/j.cbpb.2020.110506 |
| Popis: | Vitamin D is an important regulator of calcium and phosphorus homeostasis in animals. It can be acquired from the diet or synthesised de novo when skin is exposed to UVb. Vitamin D deficiency can lead to a complex of diseases collectively called metabolic bone disease (MBD). Diurnal lizards without access to UVb are prone to develop vitamin D deficiency, even when dietary vitamin D3 is provided. A trial was conducted to determine whether juvenile nocturnal lizards require access to UVb to prevent vitamin D deficiency. All leopard geckos (Eublepharis macularius) were supplemented with dietary vitamin D3. One group was exposed to low level UVb radiation (33–51 μW/cm2) from hatching until 6 months of age and a second group remained unexposed. Animals were fed ad libitum and their growth and weight gain compared with non-exposed controls. At the end of the trial, blood samples were analysed for vitamin D3 metabolites. The concentration of the vitamin D3 metabolite, 25(OH)D3, was higher in UVb exposed animals (61 ± 20 vs. 38 ± 8 nmol/L), confirming cutaneous synthesis with UVb exposure. Growth and weight gain were similar in both groups, and this, together with the absence of clinical symptoms, suggests that dietary vitamin D3 alone can meet the vitamin D requirements for growth of this nocturnal gecko, during the first six months of life. It remains to be investigated whether the higher vitamin D metabolite levels holds other health benefits for this species, such as improved bone density or immune response. |
| Databáze: | OpenAIRE |
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