B‐Type Natriuretic Peptide Predicts Postdischarge Prognosis in Elderly Patients Admitted Due to Cardiogenic Pulmonary Edema
| Autor: | P. Giovinazzo, Federica Noventa, Nadia Aspromonte, Alessandra Fontebasso, Loredano Milani, Carolina Prevaldi, Emanuele Carbonieri, Alessandra D'Eri, Sabrina Barro, Roberto Valle |
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| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty Multivariate analysis medicine.drug_class Pulmonary Edema Comorbidity Patient Readmission Risk Assessment Predictive Value of Tests Internal medicine Natriuretic Peptide Brain medicine Natriuretic peptide Humans Aged Retrospective Studies Aged 80 and over Heart Failure business.industry Health Policy Hazard ratio Retrospective cohort study Prognosis medicine.disease Pulmonary edema Hospitalization ROC Curve Heart failure Predictive value of tests Multivariate Analysis Cardiology Geriatrics and Gerontology Cardiology and Cardiovascular Medicine business Gerontology |
| Zdroj: | The American Journal of Geriatric Cardiology. 15:202-207 |
| ISSN: | 1751-715X 1076-7460 |
| DOI: | 10.1111/j.1076-7460.2006.04830.x |
| Popis: | To examine the prognostic role of predischarge B-type natriuretic peptide (BNP) levels in elderly patients admitted to the hospital due to cardiogenic pulmonary edema, 203 patients consecutively admitted to the Heart Failure Unit of the Cardiology Department were retrospectively evaluated. The primary clinical end point selected was a combination of: 1) deaths; plus 2) readmissions to the hospital for heart failure in the 6 months after discharge. Thirty-one deaths (15.3%) and 44 readmissions for heart failure (21.7%) were recorded. Cox multivariate regression analysis confirmed that BNP cutoff values (identified on receiver-operated curve analysis) are the most accurate predictor of events. Hazard ratios (HRs) increased from the lowest, for BNPor = 200 pg/mL (HR=1), through BNP 201-499 pg/mL (HR=2.3200; p=0.0174), to the highest, for BNPor = 500 pg/mL (HR=3.6233; p=0.0009). This study demonstrates that BNP is useful in predischarge risk stratification of elderly patients with cardiogenic pulmonary edema. |
| Databáze: | OpenAIRE |
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