Natural killer T cells: innate lymphocytes positioned as a bridge between acute and chronic inflammation?
| Autor: | Lisa M. Fox, Jenny E. Gumperz, Subramanya Hegde |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Inflammation
ZAP70 Immunology Antigen-Presenting Cells Biology Natural killer T cell Microbiology Article Natural killer cell Interleukin 21 Infectious Diseases medicine.anatomical_structure CD1D medicine biology.protein Humans Natural Killer T-Cells Cytotoxic T cell lipids (amino acids peptides and proteins) IL-2 receptor Glycolipids Antigen-presenting cell |
| Zdroj: | Microbes and Infection. 12:1125-1133 |
| ISSN: | 1286-4579 |
| DOI: | 10.1016/j.micinf.2010.08.011 |
| Popis: | Natural killer T cells are an innate population of T lymphocytes that recognize antigens derived from host lipids and glycolipids. In this review, we focus on how these unique T cells are positioned to influence both acute and chronic inflammatory processes through their early recruitment to sites of inflammation, interactions with myeloid antigen presenting cells, and recognition of lipids associated with inflammation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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