GH release after GHRH plus arginine administration in obese and overweight women with polycystic ovary syndrome
| Autor: | Stefano Palomba, A. Colao, Carmela Nappi, G. Lombardi, Libuse Tauchmanovà, C. Dentico, Francesco Orio, T. Russo, Charles Sultan, Silvia Savastano, Fulvio Zullo |
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| Přispěvatelé: | Orio, F., Palomba, Stefano, Colao, Annamaria, Russo, T., Dentico, C., Tauchmanovà, L., Savastano, Silvia, Nappi, Carmine, Sultan, C., Zullo, F., Lombardi, Gaetano |
| Jazyk: | angličtina |
| Rok vydání: | 2003 |
| Předmět: |
Adult
medicine.medical_specialty endocrine system diseases Endocrinology Diabetes and Metabolism arginine Overweight Growth Hormone-Releasing Hormone Basal (phylogenetics) Endocrinology Sex hormone-binding globulin Waist–hip ratio GHRH Sex Hormone-Binding Globulin Internal medicine medicine Humans Testosterone Obesity Insulin-Like Growth Factor I Progesterone Adaptor Proteins Signal Transducing Estradiol biology Dehydroepiandrosterone Sulfate Human Growth Hormone business.industry 17-alpha-Hydroxyprogesterone Calcium-Binding Proteins nutritional and metabolic diseases Blood Proteins Luteinizing Hormone medicine.disease Polycystic ovary Growth hormone secretion Prolactin GH polycystic ovary syndrome biology.protein Intercellular Signaling Peptides and Proteins Female Follicle Stimulating Hormone medicine.symptom business Body mass index |
| Zdroj: | Scopus-Elsevier |
| Popis: | Few and unclear data are available in the literature about the relationship between impairment of GH/IGF-I axis and polycystic ovary syndrome (PCOS). This study was aimed to evaluate the basal GH and IGF- levels, and GH release after challenge test in obese and overweight women with PCOS. Thirty patients with PCOS and other 30 healthy women matched for age, body mass index (BMI) and waist-hip ratio (WHR) were studied. Serum follicle-stimulating hormone (FSH), LH, PRL, E2, P, 17OH-progesterone (17OH-P), total T, delta4, DHEA-S, SHBG, GH and IGF-I levels were evaluated in each subject. A GHRH plus arginine challenge test was performed in all subjects. After provocative test, in PCOS and control women the GH levels were significantly (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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