Pancreatic Islet Stereology: Estimation of Beta Cells Mass

Autor:	Carlos Alberto Mandarim-de-Lacerda, Marcia Barbosa Aguila, Thatiany de Souza Marinho
Rok vydání:	2019
Předmět:	Pancreatic islet Beta cell Cell biology business.industry Stereology Medicine Obesity Anatomy business
Zdroj:	International Journal of Morphology v.37 n.4 2019 SciELO Chile CONICYT Chile instacron:CONICYT
ISSN:	0717-9502
DOI:	10.4067/s0717-95022019000401331
Popis:	SUMMARY: Obesity and its comorbidities are becoming epidemic in the Western world. Beta cell mass estimation is an important indicator to track the progression of insulin resistance/type 2 diabetes, particularly in experimental studies, where it can be performed with stereological tools in an unbiased way. In this work, we present a simple protocol that can contribute to doing the practice of estimating the mass of beta cells more frequent and reproducible. As with any quantitative study, the necessary precautions regarding sampling and randomness must be respected.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a2b0bd090c7c90e0bd00c2e42d9337 https://doi.org/10.4067/s0717-95022019000401331 Zobrazit plný text záznamu Plný text ve formátu PDF