Significance of rare variants in genes involved in the pathogenesis of Lynch syndrome

Autor:	Raffaella Liccardo, Matilde Lambiase, Antonio Nolano, Marina De Rosa, Paola Izzo, Francesca Duraturo
Rok vydání:	2021
Předmět:	Genetics Humans Microsatellite Instability General Medicine Genetic Testing Colorectal Neoplasms Hereditary Nonpolyposis DNA Mismatch Repair Germ-Line Mutation
Zdroj:	International journal of molecular medicine. 49(6)
ISSN:	1791-244X
Popis:	The molecular characterization of patients with Lynch syndrome (LS) involves germline testing to detect a deleterious mutation in one of the genes of the mismatch repair (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19c3bd4cdbcd9c734eecfe36bcfdf12 https://pubmed.ncbi.nlm.nih.gov/35475445 Zobrazit plný text záznamu