Skin extensibility and consistency in patients with Ehlers-Danlos syndrome and benign joint hypermobility syndrome

Autor: Jukka S. Jurvelin, B Hansen, P H Duhn, Birgit Juul-Kristensen, T Kobayasi, Jari Arokoski, S Ullman, Lars Remvig
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Remvig, L, Duhn, P H, Ullman, S, Kobayasi, T, Hansen, B, Juul-Kristensen, B, Jurvelin, J S & Arokoski, J 2009, ' Skin extensibility and consistency in patients with Ehlers-Danlos syndrome and benign joint hypermobility syndrome ', Scandinavian Journal of Rheumatology, vol. 38, no. 3, pp. 227-30 . https://doi.org/10.1080/03009740802520714
DOI: 10.1080/03009740802520714
Popis: OBJECTIVES: The reproducibility of clinical tests for skin extensibility and consistency, essential for differentiating between types of Ehlers-Danlos syndrome (EDS) and benign joint hypermobility syndrome (BJHS), is unknown. Paraclinical methods may provide objective differential diagnostic methods. METHODS: Six EDS, 11 BJHS, and 19 controls completed the trial. We analysed the overall inter-examiner agreement on clinical tests for skin extensibility and consistency, in addition to analyses on suction cup (SC) and soft tissue stiffness meter (STSM) methods. RESULTS: Overall agreement on tests for skin extensibility and consistency varied between 0.44 and 0.72. Extensibility evaluated by SC showed an insignificant difference between EDS patients and controls (p = 0.056). Consistency evaluated by STSM showed significant differences (p = 0.001). CONCLUSIONS: Overall inter-examiner agreement on clinical tests for skin extensibility and consistency was below 0.80, which was required a priori to conduct a reproducibility study. Further refinement of tests and a training phase are necessary. The SC and STSM results are encouraging but must be reproduced in a larger study population.
Databáze: OpenAIRE