Dense, shape‐optimized posterior 32‐channel coil for submillimeter functional imaging of visual cortex at 3T

Autor: Andre van der Kouwe, Reza Farivar, Boris Keil, Filip Grigorov, Lawrence L. Wald
Jazyk: angličtina
Rok vydání: 2015
Předmět:
ocular dominance columns
Channel (digital image)
Computer science
accelerated EPI
Signal-To-Noise Ratio
orientation columns
Sensitivity and Specificity
030218 nuclear medicine & medical imaging
Hardware and Instrumentation – Full Papers
03 medical and health sciences
Magnetics
0302 clinical medicine
Nuclear magnetic resonance
medicine
Radiology
Nuclear Medicine and imaging
Computer vision
Shape optimization
parallel imaging
Visual Cortex
Orientation column
Brain Mapping
Full Paper
phased‐array
business.industry
Phantoms
Imaging
Brain atlas
fMRI
Reproducibility of Results
Equipment Design
Image Enhancement
Magnetic Resonance Imaging
3. Good health
Functional imaging
Equipment Failure Analysis
Visual cortex
medicine.anatomical_structure
Electromagnetic coil
shape optimization
functional MRI
Computer-Aided Design
Evoked Potentials
Visual
Artificial intelligence
business
030217 neurology & neurosurgery
Ocular dominance column
Zdroj: Magnetic Resonance in Medicine
ISSN: 1522-2594
0740-3194
Popis: Purpose Functional neuroimaging of small cortical patches such as columns is essential for testing computational models of vision, but imaging from cortical columns at conventional 3T fields is exceedingly difficult. By targeting the visual cortex exclusively, we tested whether combined optimization of shape, coil placement, and electronics would yield the necessary gains in signal-to-noise ratio (SNR) for submillimeter visual cortex functional MRI (fMRI). Method We optimized the shape of the housing to a population-averaged atlas. The shape was comfortable without cushions and resulted in the maximally proximal placement of the coil elements. By using small wire loops with the least number of solder joints, we were able to maximize the Q factor of the individual elements. Finally, by planning the placement of the coils using the brain atlas, we were able to target the arrangement of the coil elements to the extent of the visual cortex. Results The combined optimizations led to as much as two-fold SNR gain compared with a whole-head 32-channel coil. This gain was reflected in temporal SNR as well and enabled fMRI mapping at 0.75 mm resolutions using a conventional GRAPPA-accelerated gradient echo echo planar imaging. Conclusion Integrated optimization of shape, electronics, and element placement can lead to large gains in SNR and empower submillimeter fMRI at 3T. Magn Reson Med, 2015. © 2015 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Databáze: OpenAIRE
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