Towards reconstructing a metabolic tree of life
Autor: | Marina Marcet-Houben, Santiago Garcia-Vallvé, Antoni Romeu, Pere Puigbò |
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Jazyk: | angličtina |
Rok vydání: | 2007 |
Předmět: |
dendogram
Ecology Firmicutes Tree of life (biology) Species distribution Dendrogram enzymes species General Medicine Computational biology Symbiobacterium thermophilum Biology Hypothesis biology.organism_classification Actinobacteria Clostridia taxonomy fluids and secretions Similarity (network science) metablic pathways bacteria |
Zdroj: | Bioinformation |
ISSN: | 0973-2063 |
Popis: | Using information from several metabolic databases, we have built our own metabolic database containing 434 pathways and 1157 different enzymes. We have used this information to construct a dendrogram that demonstrates the metabolic similarities between 282 species. The resulting species distribution and the clusters defined in the tree show a certain taxonomic congruence, especially in recent relationships between species. This dendrogram is another representation of the tree of life, based on metabolism that may complement the trees constructed by other methods. For example, the metabolic dissimilarity we demonstrate between Symbiobacterium thermophilum (previously defined as Actinobacteria) and the other Actinobacteria species, and the metabolic similarity between S. thermophilum and Clostridia, combined with other evidence, suggest that S. thermophilum may be re-classified as Firmicutes, Clostridia. |
Databáze: | OpenAIRE |
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