Utility of Induced Sputum in Routine Clinical Practice
| Autor: | Eder Mateus, Laura Sebastián, Montserrat Torrejón, Silvia Barril, Gianluca Cotta, Vicente Plaza, Astrid Crespo, David Ramos-Barbón |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Referral Clinical Decision-Making Hospital Departments Induced sputum Leukocyte Count 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans 030212 general & internal medicine Aged Retrospective Studies Asthma Inflammation Saline Solution Hypertonic business.industry Nebulizers and Vaporizers Sputum Reflux Retrospective cohort study General Medicine Middle Aged medicine.disease respiratory tract diseases Surgery Chronic cough Pulmonology Cough 030228 respiratory system Gastroesophageal Reflux Female medicine.symptom Salivation business |
| Zdroj: | Archivos de Bronconeumología (English Edition). 52:250-255 |
| ISSN: | 1579-2129 |
| DOI: | 10.1016/j.arbr.2016.03.008 |
| Popis: | Objective To determine the general and specific utility in diagnosis and/or treatment of induced sputum (IS) inflammatory cell counts in routine clinical practice. Methods Retrospective study of 171 patients referred for clinical sputum induction over a 1-year period in the pulmonology department of a referral hospital. Independent observers established whether the information provided by IS inflammatory cell count was useful for making diagnostic and therapeutic decisions. Results The most frequent reasons for determination of IS inflammatory cell count were: asthma 103 (59.20%); uncontrolled asthma 34 (19.54%); chronic cough 19 (10.9%), and gastroesophageal reflux 15 (8.6%). In 115 patients (67.3%) it was generally useful for diagnosis and/or treatment; in 98 patients (57.3%) it provided diagnostic information and in 85 patients (49.7%) it assisted in therapeutic decision-making. In asthma, uncontrolled asthma, chronic cough and gastroesophageal reflux, the results were useful in 71.8%, 67.6%, 47.4% and 60%, respectively. Conclusion The information provided by IS inflammatory cell count is extremely useful in clinical practice, especially in asthma and chronic cough. These results may justify the inclusion of the IS technique in pulmonology departments and asthma units of referral centers. |
| Databáze: | OpenAIRE |
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