Roles of Microembolus and Plasma D-dimer in Evaluating the Warfarin Anticoagulant Therapy Efficacies for Patients with Atrial Fibrillation
| Autor: | Xiao-Ping Lu, Xiao-Ying Zhao, Li-Jiao Jiang, Bing Wang, Yun Xu, Fang Wang |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Embolism Gastroenterology Fibrin Fibrinogen Degradation Products 03 medical and health sciences 0302 clinical medicine Internal medicine D-dimer Atrial Fibrillation medicine Microembolus Humans 030212 general & internal medicine Aged Retrospective Studies Aged 80 and over Dose-Response Relationship Drug business.industry Warfarin Anticoagulants Atrial fibrillation Retrospective cohort study General Medicine Middle Aged medicine.disease Dose–response relationship Treatment Outcome Anticoagulant therapy 030220 oncology & carcinogenesis Surgery Female Cardiology and Cardiovascular Medicine business Biomarkers medicine.drug Follow-Up Studies |
| Zdroj: | The heart surgery forum. 22(1) |
| ISSN: | 1522-6662 |
| Popis: | Background: To investigate the roles of microembolus and plasma D-dimer in evaluating the warfarin anticoagulant therapy efficacies for patients with atrial fibrillation (AF). Methods: Fifty-six AF patients were treated with aspirin antiplatelet therapy (Group ASP) and forty AF patients were treated with warfarin anticoagulant therapy (Group WAR). The microemboli and plasma D-dimer in these two groups were monitored and compared before and after treatment. Results: Group ASP had 21 and 17 cases with positive microemboli before and after treatment, respectively, and there was no significant difference in the detection rate of microemboli before and after treatment; Group WAR had 14 and 5 cases with positive microemboli before and after treatment, respectively, and the detection rate of microemboli was significantly reduced after treatment. The levels of plasma D-dimer in the two groups were significantly reduced after treatment (327±73 µg/L vs 235±61 µg/L and 313±81 µg/L vs 170±67 µg/L, respectively, P |
| Databáze: | OpenAIRE |
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