Therapeutic drug monitoring using saliva as matrix: an opportunity for linezolid, but challenge for moxifloxacin

Autor:	Simone H J van den Elsen, Tjip S. van der Werf, Mireille A. Wessels, Samiksha Ghimire, Daan J Touw, Mathieu S. Bolhuis, Erwin M Jongedijk, Jan-Willem C. Alffenaar, Onno W. Akkerman
Přispěvatelé:	Microbes in Health and Disease (MHD), Pharmaceutical Analysis, Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE), Groningen Research Institute for Asthma and COPD (GRIAC), Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Nanomedicine & Drug Targeting, Medicinal Chemistry and Bioanalysis (MCB)
Rok vydání:	2019
Předmět:	Pulmonary and Respiratory Medicine Adult Male Saliva Moxifloxacin Antitubercular Agents Microbial Sensitivity Tests Pharmacology TUBERCULOSIS Matrix (chemical analysis) 03 medical and health sciences chemistry.chemical_compound fluids and secretions 0302 clinical medicine stomatognathic system Tuberculosis Multidrug-Resistant medicine Humans heterocyclic compounds 030212 general & internal medicine Prospective Studies Netherlands medicine.diagnostic_test business.industry Linezolid biochemical phenomena metabolism and nutrition Middle Aged bacterial infections and mycoses FLUID TB 030228 respiratory system chemistry Therapeutic drug monitoring Female Drug Monitoring business medicine.drug
Zdroj:	European Respiratory Journal, 55(5):1901903. EUROPEAN RESPIRATORY SOC JOURNALS LTD
ISSN:	1399-3003 0903-1936
Popis:	Therapeutic drug monitoring using saliva as matrix is a suitable alternative for serum therapeutic drug monitoring of linezolid, but not for moxifloxacin due to a high variability in saliva-plasma ratioshttp://bit.ly/2NIYdz7
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17e60386be16651e19eb910b7a956e1 https://pubmed.ncbi.nlm.nih.gov/31980497 Zobrazit plný text záznamu