The case for strategic international alliances to harness nutritional genomics for public and personal health

Autor: Jean-Philippe Jais, Lin He, Matthew A. Roberts, Michael C. Archer, Mitchell M. Kanter, Gertrud U. Schuster, Taesun Park, Kaisa Poutanen, Bruce German, Jose M. Ordovas, Warren C. McNabb, Susan J. Fairweather-Tait, Ivana Beatrice Manica da Cruz, Paul Trayhurn, Craig A. Cooney, Su-Ju Lin, Rosane Caetano, Denis R. Lauren, Willard J. Visek, Michael Mayne, Craig H Warden, Ricardo Uauy, Dolores Corella, Wim H. M. Saris, Bruce R. Korf, Ruth Chadwick, Jim Kaput, Norma Ana Pensel, Frans van der Ouderaa, John K. Wiencke, Ruan M. Elliott, Ben van Ommen, Jan-Åke Gustafsson, Yangsoo Jang, Michael J. Gibney, Troy Duster, Sven O. E. Ebbesson, Ruth Birk, Francisco Pérez-Jiménez, Michael Fenech, David Castle, David W. Krempin, Ronald M. Krauss, Kenneth S. Kornman, Jae-Kwan Hwang, Kenneth H. Brown, Rosalynn Gill-Garrison, Lynnette R. Ferguson, Claudine Junien, Kent J. Bradford, Gillies Peter John, John C. Mathers, Xi Zhao-Wilson, Michael Müller, John L. Hartman, Yuri Nikolsky, Jong Ho Lee, Berthold Koletzko, Sue Southon, Karine Clément, Andrew N. Shelling, Peter J. van Bladeren, Jim Felton, John W. Finley, Stephen L. Clarke, Bruce N. Ames, Hans Joost, Gilbert A. Leveille, Stephen Barnes, Jean-Daniel Zucker, Bradford Towne, Warren A. Kibbe, Nancy Fogg-Johnson, Peter Morgan, Raymond L. Rodriguez, E. Shyong Tai, Amelia Bartholomew, Kevin Dawson, Wasyl Malyj, Jack Winkler, Dominique Langin, John A. Milner, Rick Weiss, Lindsay H. Allen, Hannelore Daniel, George L. Wolff, Artemis P. Simopoulos
Přispěvatelé: TNO Kwaliteit van Leven
Jazyk: angličtina
Rok vydání: 2005
Předmět:
Knowledge management
Nutritional genomics
Biomedical Research
genetic association
030309 nutrition & dietetics
genotype
International Cooperation
Medicine (miscellaneous)
Variation (Genetics)
Human genetic variation
medical research
gene–nutrient interactions
Voeding
Metabolisme en Genomica
Eating
Nutrigenomics
environmental factor
genetic variability
Global health
Nutritional Physiological Phenomena
Health diaparities
immune function
2. Zero hunger
0303 health sciences
Nutrition and Dietetics
strategic international alliances
article
Genomics
diabetes-related traits
dietary fiber
Health equity
Metabolism and Genomics
3. Good health
messenger-rna
Health
Metabolisme en Genomica
Nutrition
Metabolism and Genomics
health diaparities
medicine.medical_specialty
Research program
hapmap project
population stratification
heredity
phenotype
Biology
Environment
Strategic international alliances
nutritional health
03 medical and health sciences
Gene interaction
nutrigenomics
SDG 3 - Good Health and Well-being
Voeding
medicine
Animals
Humans
complex diseases
human
030304 developmental biology
gene identification
VLAG
Nutrition
nonhuman
business.industry
Genome
Human
Public health
Research
Genetic Variation
population genetics
Gene-nutrient interactions
cultural factor
Nutrition Physiology
Biotechnology
Disease Models
Animal
Harness
molecular genetics
business
dietary intake
public health service
coronary-heart-disease
carbohydrate ingestion
Zdroj: British Journal of Nutrition, 94(5), 623-632
ResearcherID
Kaput, J, Ordovas, J M, Ferguson, L, Poutanen, K & et al. 2005, ' The case for strategic international alliances to harness nutritional genomics for public and personal health ', British Journal of Nutrition, vol. 94, no. 5, pp. 623-632 . https://doi.org/10.1079/BJN20051585
British Journal of Nutrition, 5, 94, 623-632
British Journal of Nutrition 94 (2005) 5
ISSN: 0007-1145
Popis: Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into nutrients, antinutrients, and bioactive compounds. Results from molecular and genetic epidemiological studies indicate that dietary unbalance can alter gene-nutrient interactions in ways that increase the risk of developing chronic disease. The interplay of human genetic variation and environmental factors will make identifying causative genes and nutrients a formidable, but not intractable, challenge. We provide specific recommendations for how to best meet this challenge and discuss the need for new methodologies and the use of comprehensive analyses of nutrient-genotype interactions involving large and diverse populations. The objective of the present paper is to stimulate discourse and collaboration among nutrigenomic researchers and stakeholders, a process that will lead to an increase in global health and wellness by reducing health disparities in developed and developing countries. © The Authors 2005.
Databáze: OpenAIRE
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