A Gene Expression Map for Caenorhabditis elegans
| Autor: | Jim Lund, George S. Davidson, Stuart K. Kim, Min Jiang, Andreas Eizinger, Moni Kiraly, Joshua M. Stuart, Brian N. Wylie, Kyle Duke |
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| Rok vydání: | 2001 |
| Předmět: |
Male
DNA Complementary Databases Factual Pair-rule gene Gene Expression Biology Gene density Gene cluster Animals Caenorhabditis elegans Gene Genes Helminth Oligonucleotide Array Sequence Analysis Neurons Genetics Regulation of gene expression Genome Multidisciplinary Gene Expression Profiling Muscles Computational Biology Nucleic Acid Hybridization Genomics Helminth Proteins biology.organism_classification Spermatozoa Intestines Gene expression profiling Gene Expression Regulation DNA Transposable Elements Oocytes Female RNA Helminth DNA microarray Algorithms Software |
| Zdroj: | Science. 293:2087-2092 |
| ISSN: | 1095-9203 0036-8075 |
| DOI: | 10.1126/science.1061603 |
| Popis: | We have assembled data from Caenorhabditis elegans DNA microarray experiments involving many growth conditions, developmental stages, and varieties of mutants. Co-regulated genes were grouped together and visualized in a three-dimensional expression map that displays correlations of gene expression profiles as distances in two dimensions and gene density in the third dimension. The gene expression map can be used as a gene discovery tool to identify genes that are co-regulated with known sets of genes (such as heat shock, growth control genes, germ line genes, and so forth) or to uncover previously unknown genetic functions (such as genomic instability in males and sperm caused by specific transposons). |
| Databáze: | OpenAIRE |
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