Facilitators of HCV treatment adherence among people who inject drugs: a systematic qualitative review and implications for scale up of direct acting antivirals

Autor: Joseph D. Tucker, Weiping Cai, Paul A. Volberding, Jessica Mao, Qingyan Ma, Zachary C. Rich, Carissa Chu, Kali Zhou
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Databases
Factual
Treatment adherence
Alternative medicine
8.1 Organisation and delivery of services
Hepatitis
0302 clinical medicine
7.1 Individual care needs
Epidemiology
Medicine
030212 general & internal medicine
Substance Abuse
Intravenous
media_common
Hepatitis C virus
lcsh:Public aspects of medicine
Liver Disease
Substance Abuse
Hepatitis C
Infectious Diseases
Public Health and Health Services
HIV/AIDS
030211 gastroenterology & hepatology
Public Health
Intravenous
Infection
Health and social care services research
Research Article
medicine.medical_specialty
Drug Abuse (NIDA Only)
media_common.quotation_subject
Chronic Liver Disease and Cirrhosis
Antiviral Agents
03 medical and health sciences
Databases
Social Facilitation
Hepatitis - C
Clinical Research
Behavioral and Social Science
Humans
Factual
business.industry
Addiction
Public health
Public Health
Environmental and Occupational Health
lcsh:RA1-1270
Emerging Infectious Diseases
Good Health and Well Being
Injection drug use
Family medicine
Hcv treatment
Patient Compliance
Management of diseases and conditions
Biostatistics
business
Digestive Diseases
Qualitative research
Zdroj: BMC Public Health
BMC public health, vol 16, iss 1
BMC Public Health, Vol 16, Iss 1, Pp 1-10 (2016)
ISSN: 1471-2458
Popis: Background While the public health benefits of new HCV treatments depend on treatment adherence, particularly among people who inject drugs (PWID), several social and medical factors can jeopardize treatment adherence. The aim of this study is to examine the qualitative literature on facilitators to HCV treatment adherence among PWID. Methods We searched six databases to identify qualitative research studies on HCV treatment adherence facilitators among PWID. Two reviewers independently extracted and analyzed data using PRISMA guidelines and the CASP tool to evaluate study quality. Results From ten studies representing data from 525 participants, three major themes emerged across studies: logistical facilitators within health systems enhanced HCV treatment adherence, positive social interactions between PWID and staff provided positive feedback during treatment, and HCV treatment may complicate the addiction recovery process. Conclusions Although PWID face several barriers to adherence, we identified treatment adherence facilitators that could be incorporated into clinical practice. Electronic supplementary material The online version of this article (doi:10.1186/s12889-016-3671-z) contains supplementary material, which is available to authorized users.
Databáze: OpenAIRE
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