Assessing Survival and Grading the Severity of Complications in Octogenarians Undergoing Pulmonary Lobectomy
| Autor: | Ralph W. Aye, Eric Vallières, Andrew F Feczko, Alexander S. Farivar, Elizabeth McKeown, Jed A. Gorden, Brian E. Louie, Jennifer L. Wilson |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Lung Neoplasms Article Subject medicine.medical_treatment Population 030204 cardiovascular system & hematology Severity of Illness Index 03 medical and health sciences Pneumonectomy Diseases of the respiratory system 0302 clinical medicine Postoperative Complications Carcinoma Non-Small-Cell Lung Severity of illness medicine Humans education Lung cancer Grading (tumors) Retrospective Studies Aged 80 and over education.field_of_study RC705-779 business.industry Retrospective cohort study Perioperative medicine.disease United States Surgery 030220 oncology & carcinogenesis Female business Complication Research Article |
| Zdroj: | Canadian Respiratory Journal, Vol 2017 (2017) Canadian Respiratory Journal |
| ISSN: | 1916-7245 1198-2241 |
| Popis: | Introduction. Octogenarians are at increased risk for complications after lung resection. With alternatives such as radiation, understanding the risks of surgery and associated survival are valuable. Data grading the severity of complications and long-term survival in this population is lacking. We reviewed our experience with lobectomy in octogenarians, grading complications using a validated thoracic morbidity and mortality schema. Methods. We retrospectively reviewed consecutive patients aged ≥80 undergoing lobectomy between 2004 and 2012. Demographics, clinical/pathologic stage, complications, recurrence, and mortality were collected. Complications were graded by the Seely thoracic morbidity and mortality model. Results. 45 patients (mean age 82.2 years) were analyzed. The majority of patients (28/45, 62%) were clinical stage IA/IB. 62% (28/45) of patients experienced a complication. Only 15.6% (7/45) were considered significantly morbid (≥ grade IIIB) per the Seely model. Perioperative mortality was 2% and half of patients were living at a follow-up of 53 months. Overall five-year survival was 52%. Conclusions. In carefully selected octogenarians, lobectomy carries a 15.6% rate of significantly morbid complications with encouraging overall survival. These data provide the basis for a more complete discussion with patients regarding lobectomy for lung cancer. |
| Databáze: | OpenAIRE |
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